11. Peptides Part 2: My 6 Favorite Kinds!

If you're already on HRT, lifting, eating protein, and sleeping — and still not getting the results you expect — this episode is your next layer. Part 2 of our three-part peptide series, Dr. Mary Pines walks through her six favorite peptides: what they do, who they're for, and how she actually uses them with clients.

This isn't a survey of everything that exists. It's the shortlist Mary reaches for most often in practice — chosen based on two decades of biomedical science, years of peptide conference data, and her current A4M advanced peptide certification.

In this episode:

  • BPC-157: the gut and injury repair all-star, how it works orally vs. injected, and why it's banned in professional sports

  • TB-500: the antifibrotic partner that helps tissues heal cleanly — and how the BPC-157 + TB-500 duo works synergistically

  • Thymosin alpha-1: the immune peptide used as a drug in over 20 countries, and why perimenopause disrupts immune balance in ways most doctors don't explain

  • CJC-1295 + ipamorelin: how to support growth hormone, deep sleep, muscle, and bone without the risks of synthetic GH

  • GLP-1s: what three generations of these peptides actually do, why the media narrative was wrong, the case for microdosing, and what the 2026 semaglutide patent expiry means for access

  • Selank + Semax: the Russian-developed brain peptides for anxiety, cognitive fatigue, and post-viral recovery

  • GHK-Cu: the copper peptide bioregulator that influences 4,000 aging-related genes — and what to actually look for in a topical

Additional Podcast Platforms

Listen to this episode on Apple Podcasts,Spotify, Amazon Music, iHeartRadio, AudiblePodcast Addict, PocketCasts, CastboxYouTubeGoodpodsCastro, or on your favorite podcast platform.

Links & Resources

About Dr. Mary, Blog, Shop & more at DrMaryPines.com

Her signature Better Beyond 40 Formula is designed to help peri/menopausal women (35-65) rebalance their bodies, overcome hormonal symptoms & lose weight using natural, science-based approaches they won't hear about in most doctor's offices or online. 

👉 Watch the FREE MasterClass to learn more & see if it might be a fit for you.

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You can watch each episode on YouTube

You can find the transcript of this episode here. Transcripts of all episodes can be found here.

Mentions in this Episode

Vladimir Khavinson — Russian scientist, original BPC-157 researcher, referred to as the "godfather of peptides"

A4M — American Academy of Anti-Aging Medicine for peptide certification (including Dr Mary’s) and peptide conferences

Zadaxin — drug name for Thymosin alpha-1, used in multiple countries for chronic infection and immune conditions

Dr. Mary Claire Haver hosts and excellent 2-part Glp-1 episode with Dr. Rocio Salas-Whelan — Glp-1 expert, guest on Dr. Mary Claire Haver's podcast (Webby Award nominated episode)

Dr. Tina Moore — advocate for Glp-1 microdosing protocols & use of Glp-1s for much more than weight loss

Ozempic, Wegovy — semaglutide brand names

Mounjaro, Zepbound — tirzepatide brand names

Retatrutide — triple agonist Glp-1, not FDA approved, discussed as V3.0

Exenatide — first Glp-1 drug, approved 2005 for type 2 diabetes

Selank — anxiolytic brain peptide, derived from tuftsin fragment

Semax — cognitive peptide derived from ACTH fragment

GHK-Cu research paper: "GHK and DNA: Resetting the Human Genome to Health"

Vitali — topical GHK-Cu product line Dr Mary recommends

Infiniwell — topical GHK-Cu product line Dr Mary recommends. Shiny new discount code!

 
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10. Part 1: Peptides 101 - What, Why & How?!